PATROL: Prostate Cancer Screening for People AT Genetic Risk FOr Aggressive Disease
Status: Recruiting
Location: See all (8) locations...
Intervention Type: Other, Procedure
Study Type: Observational
SUMMARY
This study investigates ways to detect prostate cancer earlier in people at genetic risk for disease that forms, grows, or spreads quickly (aggressive). Studying samples of blood, urine, and/or tissue in the laboratory may help doctors further understand the genetics of prostate cancer and help identify ways to detect cancer earlier, thereby improving treatment and methods of early detection in the future.
Eligibility
Participation Requirements
Sex: Male
Minimum Age: 40
Healthy Volunteers: t
View:
• People with prostates ≥40 years of age
• Documented germline pathogenic variant in known or suspected genes associated with prostate cancer risk.
Locations
United States
California
City of Hope
NOT_YET_RECRUITING
Duarte
University of California, San Francisco
NOT_YET_RECRUITING
San Francisco
Illinois
Northwestern
RECRUITING
Chicago
Massachusetts
Massachusetts General Hospital
NOT_YET_RECRUITING
Boston
Oregon
OHSU Knight Cancer Institute
RECRUITING
Portland
Pennsylvania
University of Pennsylvania/Abramson Cancer Center
RECRUITING
Philadelphia
Texas
University of Texas Health Science Center at San Antonio
TERMINATED
San Antonio
Washington
Fred Hutch/University of Washington Cancer Consortium
RECRUITING
Seattle
Contact Information
Primary
Study Team Coordinator
patrol@uw.edu
206-210-4040
Time Frame
Start Date: 2020-05-21
Estimated Completion Date: 2030-08-31
Participants
Target number of participants: 450
Treatments
Screening (biospecimen collection)
Participants undergo collection of blood, urine, and/or tissue samples every 12 months, when any biopsy occurs, and if relevant, at time of curative therapy and 12 months after completion of curative therapy.
Authors
Related Therapeutic Areas
Sponsors
Collaborators: Canary Foundation, CureBRCA, National Cancer Institute (NCI)
Leads: University of Washington